Mitogen-Activated Protein Kinase 14

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 PHE-59   GLN-60  7.6 7.4 0.8 6.5 32.5 34.7 138.2
 GLN-60   SER-61  10.6 10.5 1.1 -10.6 67.8 70.0 -155.5
 SER-61   ILE-62  11.4 11.4 -3.8 -10.2 56.1 54.1 204.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-86   LEU-87  4.4 4.3 2.4 -5.8 71.2 70.8 37.8
 LEU-87   ASP-88  6.7 6.8 0.9 -4.5 140.8 141.0 39.9
 ASP-88   VAL-89  7.2 7.2 5.6 -4.1 144.2 145.3 -86.3
 VAL-89   PHE-90  6.1 6.2 -1.3 -0.2 130.0 131.0 -61.0
 VAL-89   PHE-90  6.1 6.2 -1.3 -0.2 130.0 131.0 -61.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-89   PHE-90  6.1 6.2 -1.3 -0.2 130.0 131.0 -61.0
 VAL-89   PHE-90  6.1 6.2 -1.3 -0.2 130.0 131.0 -61.0
 PHE-90   THR-91  8.2 8.2 4.9 -8.0 25.4 24.4 9.5
 THR-91   PRO-92  8.9 8.9 -4.8 -5.0 108.8 110.2 42.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LEU-104   VAL-105  8.4 8.3 6.3 -4.8 41.6 43.6 11.3
 VAL-105   THR-106  9.7 9.7 1.5 -5.2 31.1 31.5 -68.2
 THR-106   HIS-107  9.7 9.6 6.5 0.9 48.4 50.0 118.0
 HIS-107   LEU-108  11.4 11.5 5.8 28.6 92.5 101.3 -101.2
 LEU-108   MET-109  15.0 15.1 34.6 11.2 15.8 43.7 735.3
 MET-109   GLY-110  15.0 15.9 3.3 -129.3 69.2 80.3 -835.5
 GLY-110   ALA-111  18.0 19.1 16.5 60.2 123.4 90.2 -279.0

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees