Metabotropic Glutamate Receptor 2

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue i Residue i+1 Distance of hinge axis to residue i in conformer 1 (A) Distance of hinge axis to residue i in conformer 2 (A) Change in psi (i) (deg) Change in phi (i+1) (deg) Angle of psi(i) axis to hinge axis conformer 1 (deg) Angle of psi(i) axis to hinge axis conformer 2 (deg) Percentage Progress  ASP-533   GLU-534  4.2 5.6 15.8 1.7 117.7 121.4 -42.4  GLU-534   PHE-535  7.2 8.8 -12.3 -10.0 49.1 45.3 40.9  PHE-535   THR-536  9.4 10.6 10.4 54.2 130.1 104.9 -108.0  THR-536   CYS-537  7.6 8.6 -64.0 19.7 79.2 34.3 96.1  CYS-537   ALA-538  4.6 7.8 -45.2 -6.9 63.5 70.1 72.3  ALA-538   ASP-539  5.4 9.1 -31.3 41.8 47.5 48.7 -14.8  ASP-539   CYS-540  5.6 9.3 -13.5 -6.0 112.0 118.0 -25.9  CYS-540   GLY-541  7.6 9.4 -106.2 143.0 61.8 67.0 -11.0  GLY-541   LEU-542  11.3 13.1 49.2 -1.6 142.0 177.2 -132.0  LEU-542   GLY-543  12.1 14.4 169.5 144.8 77.6 114.1 20.3  TRP-545   PRO-546  8.8 8.0 -53.4 -16.5 143.6 157.0 -194.6  PRO-546   ASN-547  6.5 5.6 20.2 -15.9 73.7 76.9 -12.0  LEU-550   THR-551  5.4 2.9 27.5 50.2 43.2 40.4 230.0  THR-551   GLY-552  4.2 5.7 -72.9 -31.0 95.7 82.3 58.5  GLY-552   CYS-553  6.9 7.8 11.6 56.4 148.4 163.3 -195.5 Graph shows rotational transition at bending residues and can be used to identify hinge bending residues. Probably only informative for interdomain rotations greater than 20 degrees