DynDom - Protein Domain Motions

Atp Synthase Alpha Chain, Mitochondrial

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Atp Synthase Alpha Chain, Mitochondrial
Conformer 1 (PDB)	2hld (C)
Conformer 2 (PDB)	1h8e (C)
Window Length	7
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	401	0.75	29 - 352 354 - 369 374 - 389 427 - 454 456 - 463 486 - 491 502 - 504
2	39	0.86	353 - 353 370 - 373 390 - 426 455 - 455
3	32	0.77	464 - 485 492 - 501

Sequence

`________________________________________________________________________________________________________________________` `2hld(C) : ***NLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSGVKGMALNLEPGQVGIVLFGSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQVKAPGILP` `:` `1h8e(C) : ADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAIDGKGPIGSKARRRVGLKAPGIIP` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2hld(C) : RRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAPFTAASIGEWFR` `:` `1h8e(C) : RISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQLVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFR` `________________________________________________________________________________________________________________________` `_________________________________________________________________________________________352______________369_373_______` `2hld(C) : DNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAA` `:` `1h8e(C) : DNGKHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAA` `_________________________________________________________________________________________350______________367_371_______` `__385______________________________________426_____________________450___456__________________________485_____________50` `2hld(C) : QVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSRIGEFESSFLSYLKSNHNELLTEIREKGELSKELLASLK` `:` `1h8e(C) : QTRAMKQVAGTMKLELAQYREVAAFA----dLDAATQQLLSRGVRLTELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVISQHQALLGKIRTDGKISEESDAKLK` `__383______________________________________424_____________________448___454__________________________483_____________49` `1___________` `2hld(C) : SATESFVAT*` `:` `1h8e(C) : EIVTNFLAGFEA` `9___________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	6.8
Translation (A)	-0.1
Closure (%)	80.6
Bending Residues ( green )	352 - 354 369 - 370 373 - 374 385 - 390 426 - 427 450 - 463
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	10.0
Translation (A)	0.4
Closure (%)	100.0
Bending Residues ( green )	456 - 465 485 - 492 501 - 502
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Mixed

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