Cyclin-Dependent Kinase-2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Cyclin-Dependent Kinase-2
  Conformer 1
(PDB) 		1jst (A)
  Conformer 2
(PDB) 		1hck (A)
  Window Length 9
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 20 2.54   33 - 56
2 50 1.09   5 - 32   63 - 84
3 194 0.8   57 - 62   85 - 146   169 - 294

Sequence


           ______________________________32______________________56____62____________________84____________________________________ 
 1jst(A) : MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 
         :                                                                                                                          
 1hck(A) : MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR----tEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 
           ______________________________32______________________56____62____________________84____________________________________ 

           ________________________________________________________________________________________________________________________ 
 1jst(A) : HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTY-hEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 
         :                                                                                                                          
 1hck(A) : HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 
           ________________________________________________________________________________________________________________________ 

           __________________________________________________________                                                               
 1jst(A) : PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL                                                               
         :                                                                                                                          
 1hck(A) : PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL                                                               
           __________________________________________________________                                                               

Morph
Morph animation in progress.
Status: Initialising

This morph was created using the MorphIt_Pro protein morphing technique.
For more advanced options, right click on the model.


Show console


play backwards pause play forwards

Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 45.8 -0.3 94.1   32 - 33 Bending Region Analysis
1 3 38.9 1.9 70.9   56 - 59 Bending Region Analysis
3 2 18.4 -0.3 97.9   62 - 63   84 - 86 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 3 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 3

Movement classification:

No Contacts

PyMOL Script

Download and extract PyMOL PML script file Download