Glutamate Receptor Subunit 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Glutamate Receptor Subunit 2
  Conformer 1
(PDB) 		1fto (B)
  Conformer 2
(PDB) 		1p1o (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 37 0.52   109 - 110   116 - 119   181 - 186   192 - 212   217 - 217   257 - 259
2 141 0.33   7 - 108   218 - 256
3 75 0.4   111 - 115   120 - 180   187 - 191   213 - 216

Sequence


           _______________________________________________________________________________________________________108____115_119___ 
 1fto(B) : **TVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
         :                                                                                                                          
 1p1o(A) : NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKGTPIE 
           _______________________________________________________________________________________________________108____115_119___ 

           ______________________________________________________179____186__191__________________212__217_________________________ 
 1fto(B) : SAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
         :                                                                                                                          
 1p1o(A) : SAEDLSKQTEIAYGTTDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLN 
           ______________________________________________________179____186__191__________________212__217_________________________ 

           _________254________                                                                                                     
 1fto(B) : EQGLLDKLKNKWWYDKGEC*                                                                                                     
         :                                                                                                                          
 1p1o(A) : EQGLLDKLKNKWWYDKGECG                                                                                                     
           _________254________                                                                                                     

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Domain Pairs

Fixed Domain Moving Domain Rotation Angle Translation   (A) Closure Bending Residues  
1 2 11.8 0.2 83.3   108 - 109   217 - 220   254 - 257 Bending Region Analysis
1 3 7.9 -0.2 90.8   110 - 111   115 - 116   119 - 121   179 - 181   186 - 187   191 - 192   212 - 213   216 - 217 Bending Region Analysis
2 3 19.4 0.0 96.4   216 - 220 Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

Conformer 1 Contact:
Residue 2 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 2

Movement classification:

No Contacts

PyMOL Script

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