Mast/stem Cell Growth Factor Receptor Kit

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Mast/stem Cell Growth Factor Receptor Kit
  Conformer 1
(PDB) 		8s13 (A)
  Conformer 2
(PDB) 		8s17 (A)
  Window Length 5
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 195 0.65   596 - 602   650 - 654   673 - 807   814 - 929
2 90 0.86   571 - 595   603 - 649   655 - 672   808 - 813

Sequence


           ____________________________________595____602___________________________________________648_____________________672____ 
 8s13(A) : EVQWKVVEESnYSYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGL------mTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYG 
         :                                                                                                                          
 8s17(A) : **********NYSYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAQGLIKSDAAMTVAVKMLKPSAHSTEREALMSELKVLSYLGNHENIVNLLGACTHGGPTLVITEYCCYG 
           ____________________________________595____602___________________________________________648_____________________672____ 

           ____________________________________________________________________807___813___________________________________________ 
 8s13(A) : DLLNFLRRKRDEFVPYK--------dFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYG 
         :                                                                                                                          
 8s17(A) : DLLNFLRRKRDEFVPYKVAPEDLYKDFLTLEHLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGNITKICDFGLARDIKNDSNYVDKGNARLPVKWMAPESIFNSVYTFESDVWSYG 
           ____________________________________________________________________807___813___________________________________________ 

           ___________________________________________________________________________                                              
 8s13(A) : IFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES                                              
         :                                                                                                                          
 8s17(A) : IFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMSSPEYAPAEMYDIMKTCWDADPDKRPTFKQIVQDIEKQISES                                              
           ___________________________________________________________________________                                              

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		8.0
Translation
(A) 		-0.3
Closure
(%) 		79.3
Bending Residues
( green ) 		  595 - 596
  602 - 603
  648 - 655
  672 - 673
  807 - 808
  813 - 822
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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