Serine/threonine-Protein Kinase 6

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

  Property   Value
  Name Serine/threonine-Protein Kinase 6
  Conformer 1
(PDB) 		2c6e (A)
  Conformer 2
(PDB) 		1mq4 (A)
  Window Length 11
  Minimum ratio 1.0
  Minimum domain size 20

Domains

Domain Size Backbone RMSD
(A)		 Residues
1 157 1.32   213 - 244   246 - 382
2 83 0.99   131 - 212   245 - 245

Sequence


           _____________________________________________________________________________________212_____________________________244 
 2c6e(A) : *QWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 
         :                                                                                                                          
 1mq4(A) : RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALS 
           _____________________________________________________________________________________213_____________________________245 

           ________________________________________________________________________________________________________________________ 
 2c6e(A) : YCHSKRVIHRDIKPENLLLGSAGELKIADFGWS----------gTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 
         :                                                                                                                          
 1mq4(A) : YCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRtLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHN 
           ________________________________________________________________________________________________________________________ 

           ______________________                                                                                                   
 2c6e(A) : PSQRPMLREVLEHPWITANSSK                                                                                                   
         :                                                                                                                          
 1mq4(A) : PSQRPMLREVLEHPWITANSS*                                                                                                   
           ______________________                                                                                                   

Morph

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Domain Pairs

Property Value
Fixed Domain
( blue ) 		1
Moving Domain
( red ) 		2
Rotation Angle
(deg) 		11.5
Translation
(A) 		0.0
Closure
(%) 		88.1
Bending Residues
( green ) 		  212 - 213
  244 - 250
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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